Sunday, 18 October 2015

Low molecular weight heparin therapy | AIIMS MCQs for MD MS Preparations

Which of the following is not associated with low molecular weight heparin therapy?
A. Less chances of bleeding
B. Single dose per day
C. Easy filterability by gloinerular capillaries
D. High biological interaction to plasma proteins


Ans. C. Easy filterability by glomerular capillaries
Explanation: The
drug is metabolized by liver by an enzyme named heparinase. Due to its hepatic metabolism the drug is quickly degraded. The drug is 99% protein bound, like heparin. Both warfarin and heparin follow zero order kinetics.