Wednesday, 14 October 2015

True about cholesteaotoma is/are | PGI MCQs for MD/MS Preparations call 08699014009

True about cholesteaotoma is/are
A. It is a benign tumour
B. Metastasize to lymphnode
C. Contains cholesterol
D. Erodes the bone
E. Malignant potential



Ans. (D) Erodes the bone
• Theterm cholesteatoma is a misnomer, becasue it neither contains cholesterol crystals nor is it a tumor. This is a sac or a pocket in the middle car cleft lined by keratinised squamus epithelium and contains desquamated concentric sheets of keratin.
• Mechanism of its formation : (a) By retraction pocket formation and (b) by immigration of squamous epithelium from deeper part of the canal usually through a marginal perforation.
• The cholesteatoma sac may undergo following pathological changes
— Spontaneous healing
— Secondary infection
— The granulation tissue on the outside of the sac produces lysozymes and this gradually erodes the ossicles, eardrum, and mastoid bone.
• The nature of cholesteatoma is usually benign and does not have any malignant potential nor it metastasizes.