True about ZES (gastrinoma) | PGI MCQs for MD MS Preparations

True about ZES (gastrinoma) 
A. Gastrin levels > 1000 ng/l 
B. BAO (Basal acid output) > 15 meq/hr 
C. Somatostatin is inhibitor of HCL secretion 
D. Omeprazole is helpful 
E. Secretin increases gastrin secretion in Zollinger Ellison Syndrom


Ans. A. Gastrin levels> 1000 ng/l ; (B) BAO (Basal acid output)> 15 meq/hr;  (C) Somatostatin is inhibitor of HCL secretion ; (D) Omeprazole is helpful (E) Secretin increases gastrin secretion in zollinger Ellison Syndrome
• Most patients with Zollinger Ellison syndrome have 

— Fasting hypergastrinemia (> l000ng/L) 

— Increased basal gactric output (> 15 meq/hr) 

—Secretin increases gastrin secretion

• Proton pump inhibitor like orneprazole is helpful. 

• Somatostatin is inhibitor of HCl secretion.