Friday, 30 October 2015

Primary amebic meningoencephalitis with a rapid fulminant | AIIMS Entrance MCQ

Primary amebic meningoencephalitis with a rapid fulminant course is mostly seen in :
A. Naegleria fowleri 
B. Acanthamoeba
C. Balamuthia mandrillaris 
D. Entamoeba hartmanni

Ans. A. Naegleria fowleri
Primary amebic meningoencephalitis is a fulminant, hemorrhagic, necrotizing meningoencephalitis with a limited purulent exudate. It occurs in healthy children and young adults and is rapidly fatal. It is caused by free-living amebas, most commonly by the amebo-flagellate Naegleri fowleri.

Six well-documented survivors of N .fowleri infections have been reported based on treatment with intravenous and intrathecal amphotericin B, intravenous miconazole, and oral rifampin.