Saturday, 21 November 2015

Common site of heterotopic pancreatic tissue | MCQs for AIPGMEE

The most common site of heterotopic pancreatic tissue 

A. Stomach 
B. Jejunum 
C. Appendix 
D. Splenic hilum

Ans: A. Stomach
• Pancreatic tissue has been documented in ectopic sites in the gastrointestinal tract and even elsewhere.
• The most common site for nodules of aberrant pancreatic tissue is on the wall of the stomach, duodenum or jejunum. The nodules may be found in submucosa 75%.  and in the muscular layer or subserous coat in the remainder.
• The overall incidence and relative frequency with which it cause symptoms varies.
• Autopsy studies have found heterotopic pancreatic tissue in the duodenum in as high as 14% of individuals.
• Scattered pancreatic tissue has been found in Meckel diverticulum, gallbladder, colon, Spleen, Liver, Bile ducts, mesentery or even omentum.
• Enterogenous cysts of the thorax have been reported to contain typical pancreatic tissue, including islets.
• With the advent of widespread upper gastrointestinal endoscopy and improvements in contrast studies of the alimentary tract, ectopic pancreas of the stomach and duodenum is being more frequently recognized.
• The pathognomic radiological finding is a smooth, rounded or negative shadow with evidence of a tiny umbilication or even a small duct which may be outlined by a line of barium.
• Probably most individuals with ectopic pancreas have no symptoms whatsoever.
• However, abdominal pain surqestive of peptic ulcer disease sometimes occurs.

• Interference with gastric emptyrg by lesions situated in the pyloric region, direct production of a peptic ulcer, gastrointestinal haemorrhage, intussuscption, and development of a benign or malignant neoplasm arising in the pancreatic rest, have all been documented.