Tuesday 17 November 2015

Triflusal | AIPGMEE Preparations

Triflusal is a? 
A. Anti clotting drug
B. Anti arrthythmic drug
C. Anti platelet drug 
D. Anti inflammatory drug


Ans. C. Anti platelet drug

Triflusal is a platelet aggregation inhibitor.
Mechanism of action:
• Blocks cyclooxygenase inhibiting thromboxane A2, preventing aggregation
• Preserves vascular prostacyclin, thus promoting anti-aggregant effect
• Blocks phosphodiesterase thereby increasing cAMP concentration, thereby promoting anti-aggregant effect due to inhibition of calcium mobilization