Drug of choice for Methicillin resistant staphylococcus aureus is (MRSA)
A. Amoxicillin-Clavulanate
B. Vancomycin C. Flucloxacillin
D. Clindamycin
E. Erythromycin
Ans.
B. Vancomycin :
•
Vancomycin is the drug of choice of MRSA infections.
• Although sensitive strains may be amenable to therapy with clindamycin or
trimethoprim-sulfamethoxazole— but many strains are resistant to them.
• New antibiotic quinopristin/dalfopristin
and linezolid offer
promise for treatment of MRSA, further studies are needed for their
recommendation.
• Unfortunately, increased use
of vancomycin has resulted in emergence of both vancomycin-intermediate S.
Aureus (VISA), and Vancomycin resistant enterococci (VRE).
• Optimal therapy for VISA is unknown.
Note :Teicoplanin can also be used in MRSA infections.