Saturday 14 November 2015

Formation of Hydroxyproline and Hydroxylysine | PGI entrance Preparations

During the formation of hydroxyproline and hydroxylysine, the essential factors required is/are:-A. Pyridoxal phosphate 
B. Ascorbic acid 
C. Thiamine pyrophosphate 
D. Methylcobalamine 
E. Bioti


Ans. B. Ascorbic acid ;
• Hydroxylation of proline and lysine require
- Ascorbic acid
- a-ketoglutarate
- Ferrous iron at enzyme active site.