Thursday, 19 November 2015

Motor neuron disease MND | Medical PG Preparations

In motor neuron disease MND. all are true except? 

A. Peripheral sensory conduction velocities are normal 
B. Function of glossopharyngeal nerve is frequently affected 
C. The onset of bulbar palsy indicates a poor prognosis 
D. The abdominal reflexes are usually preserved

Ans. B. The function of the glossopharyngeal nerve is frequently affected

Some patients have vague sensory symptoms in the early stages of MND and limb pain is a surprisingly frequent problem later in the disease. However sensory signs are never present. Essential to the diagnosis is the demonstration that the peripheral sensory conduction velocities are normal. The glossopharyngeal nerve is purely sensory and so is not affected in MND, thus severe bulbar problems may be present, but palatal sensation is normal. The prognosis for life in MND once bulbar symptoms develop is usually measured in months. The abdominal reflexes, which usually disappear in the face of upper motor neurone lesions, are often strangely preserved in MND, the explanation is unknown.