Which of the following is true in iron deficiency anemia?
A. In 300 mg elemental iron given, 100mg gets absorbed
B. Reticulocytosis appearsin one to 2 weeks and then peaks in 3-4 weeks
C. Response to Rx seen in 4 weeks.
D. Decreased in absorption with improvement of symptoms.
E. Stop the Rx after normalizing the Hb
A. In 300 mg elemental iron given, 100mg gets absorbed
B. Reticulocytosis appearsin one to 2 weeks and then peaks in 3-4 weeks
C. Response to Rx seen in 4 weeks.
D. Decreased in absorption with improvement of symptoms.
E. Stop the Rx after normalizing the Hb
Ans. D.
Decreased in absorption with improvement of symptoms ;
* The average iron absorption in adult
male is 6%, in female it is 12%, but in iron deficiency can increase iron absorption in about 20% for
meat iron and five to 10% for vegeterian diet. Therefore 300 mg of elemental
iron given, only 30mg will be absorbed. With rise of hemoglobin, iron
absorption is decreased and erythropoietin stimulation also decreases.
* Typically reticulocyte count should begin to increase with 4 to 7 days after initiation of therapy and peak at 1½ week.
* An appropriate response is a return of hematocrit level half way towards the normal within 3 weeks with full return to baseline after 2 months. Iron therapy should be continued for 6-12 months after restoration of normal hematological values in order to replenish iron stores.
* Typically reticulocyte count should begin to increase with 4 to 7 days after initiation of therapy and peak at 1½ week.
* An appropriate response is a return of hematocrit level half way towards the normal within 3 weeks with full return to baseline after 2 months. Iron therapy should be continued for 6-12 months after restoration of normal hematological values in order to replenish iron stores.
