Predisposing factors for Carcinoma Oesophagus | PGI MCQs for MD MS Preparations

Predisposing factors for carcinoma oesophagus are: 
A. Tylosis 
B. Plummer vinson syndrome 
C. Reflux esophagitis 
D. Lye stricture
E. Cigarette smoking

Ans. A. Tylosis ;(B) Plummer vinson syndrome; (C) Reflux esophagitis ; (D) Lye stricture : (E) Cigarette smoking

Aetiological Factors associated with Oesophageal carcinoma
— Excess alcohol consumption — Plummer vinson syn.
— Cigarette Smoking
— Other ingested carcinogens

—? Dietary deficiencies of molybdenum, Zinc, Nitrates (converted to Nitrites), Smoked opiates

— ? Celiac sprue
—Fungal toxins in pickled vegetables

— Chronic gastric reflux (i.e. Barret’s esophagus)
—Mucosal damagefrom physicalagents foradeno carcinoma
—Hot tea
—Lye ingestion
—Radiation induced stricture
—Chronic achalasia