IgG about 80 % of antibodies in serum
IgG provides long term protection because it persists for months and years after the prescence of the antigen that has triggered their production
IgG They can leave the blood cells and move to ares of inflammation
IgG Monomer
IgG Crosses the placenta providing the foetus with passive immunity
IgG Protect against bacteris, viruses, neutralise bacterial toxins, trigger compliment protien systems and bind antigens to enhance the effectiveness of phagocytosis
IgA 10-15% of antibodies
IgA consists of two monomners joined togther
IgA The most common form of antibodies in mucous membranes and body secretion. E.g. mucus, saliva, tears, breast milk
IgA Main function is to bind antigens on microbes before they invade tissues. It aggregates the antigens and keeps them in the secretions so when the secretion is expelled, so is the antigen
IgM Make up 10-15% of Antibodies
IgM Large size so do not leave the blood vessels - Pentamer
IgM Involved in the ABO blood group antigens on the surface of RBCs
IgM Effective in aggregating antigens because it has ten binding sites
IgM Involved in compliment
IgM Enhance ingestions of cells by phagocytosis
IgD 0.2% of serum antibodies
IgD Found in te blood, lymph and especially on the surface of B cells. We have limited knowledge of their function
IgD Monomer
IgE 0.0002% of antibodies
IgE Bind to mast cells and basophils wich participate in the immune response
IgE When and antigen such as pollen binds to ths antibody, the mast cell or basophil releases histamine..
IgE Involved in allergicc reactions
IgE It attract complement and phagocytic cells..
