Saturday 7 November 2015

Post-Streptococcal Glomerulonephritis | Medical PG Preparations

Which of the following statements best describes the usual course of post-streptococcal glomerulonephritis? 

A. Most patients progress to renal failure. 
B. After resolution of the initial episode, recurrent episodes of gross hematuria are common. 
C. In most cases, hypertension and uremia subside within 1— 2 weeks. 
D. In most cases, hypertension is persistent and requires treatment.

Ans. C. In most cases, hypertension and uremia subside within 1—2 weeks.

Post-streptococcal glomerulonephritis, characterized by immune complex deposition in the glomeruli, is a self-limited disease in most patients. There is a latent period, averaging 10 days, between pharyngitis and the development of hematuria. Recovery is expected in 1—2 weeks. Unlike IgA nephropathy, recurrent episodes of gross hematuria are rare in post-streptococcal glomerulonephritis. Poststreptococcal glomerulonephritis is more common in children anti tends to be more severe when it affects adults. Hypertension and uremia resolve relatively quickly, but microscopic hematuria may persist for 6 months.