NIME Next Batch PGI Quest in Delhi from 10 August to 20 August
Antibiotic that inhibits protein synthesis is
A. Doxycycline
B. Nitrofurantoin
C. Cephalosporin
D. Penicillin
• Interfere with DNA function: Rifampin, Metronidazoic,
• Interfere with intermediary metabolism: Sulfonamides, sulfones, PAS, trimethoprim, pyrimethamine, ethambutol.
Antibiotic that inhibits protein synthesis is
A. Doxycycline
B. Nitrofurantoin
C. Cephalosporin
D. Penicillin
Ans. A. (Doxycycline)
Explanation: Mechanism of action of various antibiotics
• Inhibit cell wall synthesis: Penicillin’s, Cephalosporins, Cycloserine, Vancomycin, and Bacitracin.
• Cause leakage from cell membranes:Polypeptides—polymyxins, Colistin, and Bacitracin. Polyenes—Amphotericin B, Nystatin, and Hamycin.
Inhibit protein synthesis: Tetracyclines, Chloramphenicol, Erythromycin, Clindamycin, and Linezolid.
• Cause misreading of mRNA code and affect permeability:Aminoglycosides—Streptomycin and Gcntamycin.
• Inhibit DNA gyrase:Fluoroquinolones,
Ciprofloxacin. and others. Explanation: Mechanism of action of various antibiotics
• Inhibit cell wall synthesis: Penicillin’s, Cephalosporins, Cycloserine, Vancomycin, and Bacitracin.
• Cause leakage from cell membranes:Polypeptides—polymyxins, Colistin, and Bacitracin. Polyenes—Amphotericin B, Nystatin, and Hamycin.
Inhibit protein synthesis: Tetracyclines, Chloramphenicol, Erythromycin, Clindamycin, and Linezolid.
• Cause misreading of mRNA code and affect permeability:Aminoglycosides—Streptomycin and Gcntamycin.
• Interfere with DNA function: Rifampin, Metronidazoic,
• Interfere with intermediary metabolism: Sulfonamides, sulfones, PAS, trimethoprim, pyrimethamine, ethambutol.
