NIME Next Batch PGI Quest in Delhi from 10 August to 20 August
B. Cytochrome oxidase
C. Cytochrome P450
D. Methylation
Xenobiotics does not involve which of the following enzymes?
A. HydroxylationB. Cytochrome oxidase
C. Cytochrome P450
D. Methylation
Ans. B. (Cytochrome oxidase)
Explanation
•
This enzyme is the final component of electron transport chain.
• Xenobiotics are metabolized by monooxygenase like cytochrome P450.
• These enzymes carry out hydroxylation, deamination, dehalogenation, desulfuration, and epoxidation.
• Peroxygenation and reduction. All these reactions comprise of phase 1.
• In phase 2, the above metabolites are made water soluble.
• Xenobiotics are metabolized by monooxygenase like cytochrome P450.
• These enzymes carry out hydroxylation, deamination, dehalogenation, desulfuration, and epoxidation.
• Peroxygenation and reduction. All these reactions comprise of phase 1.
• In phase 2, the above metabolites are made water soluble.
