Raised AFP | PGI Nov 2017 Preparations MCQ

NIME Next Batch PGI Quest in Delhi from 10 August to 20 August

Raised AFP is seen in 

A. PCKD 
B. Cystic hygroma 
C. Gastroschisis 
D. Chromosomal trisomies 
E. Hepatitis

Ans. A. PCKD ; (B) Cystic hygroma ; (C) Gastroschisis; E. Hepatitis

• AFPis higher than normal in
— Liver and germ cell tumour                           — Recent or impending fetal demise
— Gastroschisis                                                   --- Fetal renal damage
— Cirrhosis, hepatitis
* In chromosal trisomies, its value is decreased.

• Extremely high level of AFP is specific for fetal congenital anomalies like meningomyelocele, PCKD, cystic hygroma and Gastroschisis