NIME Next Batch PGI Quest in Delhi from 10 August to 20 August
B. Erythromycin
C. Puromycin
D. Oligomycin
E. Penicillin
Drug clinically interacting with ribosomes to interfere with translation in bacteria
A. TetracyclineB. Erythromycin
C. Puromycin
D. Oligomycin
E. Penicillin
Ans. A. Teracycline ; (B)
Erythromycin :
• The process of translation is divided into :
— Initiation
— Elongation
— Termination.
, Streptomycin binds to the 30 S sub-units and distorts its structure, interfering with the initiation of protein synthesis.
• Tetracyclines interact with small ribosomal sub-units blocking access of the amino-acyl t-RNA to the m-RNA rihosome complex.
• Puromycin, chloramphenicol inhibits elongation.
• Clindamycin Erythromycinbindirreversibly to a site of 50S subunit of the bacterial ribosome and inhibit translation.Though puromycin inhibits translation it does not interfere with ribosomes.
• The process of translation is divided into :
— Initiation
— Elongation
— Termination.
, Streptomycin binds to the 30 S sub-units and distorts its structure, interfering with the initiation of protein synthesis.
• Tetracyclines interact with small ribosomal sub-units blocking access of the amino-acyl t-RNA to the m-RNA rihosome complex.
• Puromycin, chloramphenicol inhibits elongation.
• Clindamycin Erythromycinbindirreversibly to a site of 50S subunit of the bacterial ribosome and inhibit translation.Though puromycin inhibits translation it does not interfere with ribosomes.
