NIME Next Batch PGI Quest in Delhi from 10 August to 20 August
B. MRSA resistance is beta-lactamase independent
C. it is plasmid dependent
D. At 37°C resistance is more expressed
Ans. B. (MRSA resistance is beta-lactamase independent)
Explanation:
• Methicillin: It is highly penicillinase resistant but not acid resistant, hence must be injected. It is also an inducer of penicillinase production.
• MRSA have emerged in many areas. These are insensitive to all penicillinase-resistant penicillins and to other betalactams as well as to erythromycin, aminoglycosides, tetracyclines, etc. The MRSA have altered PBPs which do not bind penicillins.
• The drug of choice for these organisms is vancomycin/linezolid, but ciprofioxacin can also be used.
• Staph. aureus(MRSA) are not resistant to Gram-negative beta-lactamases.
Which of the followings is not correct regarding methicillin resistant staphylococci?
A. MRSA indicates resistance to all beta-lactarnasesB. MRSA resistance is beta-lactamase independent
C. it is plasmid dependent
D. At 37°C resistance is more expressed
Ans. B. (MRSA resistance is beta-lactamase independent)
Explanation:
• Methicillin: It is highly penicillinase resistant but not acid resistant, hence must be injected. It is also an inducer of penicillinase production.
• MRSA have emerged in many areas. These are insensitive to all penicillinase-resistant penicillins and to other betalactams as well as to erythromycin, aminoglycosides, tetracyclines, etc. The MRSA have altered PBPs which do not bind penicillins.
• The drug of choice for these organisms is vancomycin/linezolid, but ciprofioxacin can also be used.
• Staph. aureus(MRSA) are not resistant to Gram-negative beta-lactamases.
