Saturday, 17 June 2017

Natural prevention of cancers | PGI Nov 2017 Preparations MCQ

NIME Next Batch PGI Quest in Delhi from 10 August to 20 August


Natural prevention of cancers are/is 

A. Nitrosamines 
B. Ascorbic acid 
C. Beta carotene 
D. Vitamin D 
E. α–Tocopherol



Ans. C. Beta carotene; (D)Vitamin -D (E) α-tocopherol;
•The following agents may have role in prevention of cancers:
- Beta carotenes
-Tocopherol
- Retinol, (isotretinoin)
- Selenium
- Calcium (colon Ca)
- Isoflavones (breast Ca)
- Drugs — Tamoxifen, Raloxifene (breast Ca), NSAID (Ca colon), Finasteride (prostate Ca)
• Vit. D induces bile acid break down in vitro and may have role in protection against colon cancer.
• Calcium appears to bind bile acids in bowel lumen,inhibiting bile acid induced mucosal damage and perhaps carcinogenesis.

• Nitrosamines are present in food preservative. It may contribute to the induction of gastric carcinoma.