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B. Nephroblastoma
C. Hepatoblastoma
D. Pancreatoblastoma
Rosettes are characteristically seen in
A. RetinoblastomaB. Nephroblastoma
C. Hepatoblastoma
D. Pancreatoblastoma
Ans. A. (Retinoblastoma)
Explanation
• Retinoblastoma is the most common primary intraocular malignancy of children.
• Retinoblastoma is the most common primary intraocular malignancy of children.
•
The pathology of retinoblastoma of both hereditary and sporadic types is
identical.
•
Tumors may contain both undifferentiated and differentiated elements.
•
The former appear as collections of small, round cells with hyperchromatic
nuclei.
• In
well-differentiated tumors there are Flexner-Wintersteiner rosettes and
fleurettes reflecting photoreceptor differentiation. • It should be noted,
however, that the degree of tumor differentiation does not appear to be
associated with the prognosis.
