Monday, 19 June 2017

Hemolysis in G6PD deficiency | NEET Based MCQ

NIME Next Batch PGI Quest in Delhi from 10 August to 20 August


Hemolysis in G6PD deficiency is caused by all of the following EXCEPT 


A. Quinine 
B. Chioroquine
C. Primaquine 
D. Pyrimethamine

Ans. D. (Pyrimethamine)
Explanation
• “Antimalarials such as primaquine increase red blood cell fragility in individuals with G6PD deficiency leading to profound hemolytic anemia.”
Both chloroquine and quinine occasionally cause hemolysis in some G6PD patients. Under pyrimethamine hemolysis in G6PD has not been mentioned unlike the other drugs.