Conivaptan is use in the treatment of | Medical PG Preparations

Conivaptan is use in the treatment of? 

A. SIADH 
B. Cranial diabetes insipidus 
C. Pseudohyponatremia 
D. Nephrogenic diabetes insipidus

Ans. A. SIADH

Conivaptan is a non-peptide inhibitor of antidiuretic hormone vasopressin receptor antagonist. . It is used in the treatment for hyponatremia caused by syndrome of inappropriate antidiuretic hormone SIADH. .

Conivaptan inhibits two of the three subtypes of the vasopressin receptor V1a and V2. . Effectively, it causes iatrogenic nephrogenic diabetes insipidus.