Wednesday, 4 November 2015

Allosteric Regulatory Enzymes | Frequently Asked Medical PG topics

The glycolytic pathway requires which of the following allosteric regulatory enzymes? 
A. Glucokinase, Phosphofructokinase and pyruvate kinase 
B. Hexokinase, Aldolase and Pyruvate kinase 
C. Hexokinase, glyceraldehydes 3- phosphate dehydrogenase and enolase
D. Hexokinase Phosphofructokinase pyruvate kinase


Ans. D. Hexokinase, Phosphofructokinase and Pyruvate kinase.

> Glycolysis is conversion of glucose to pyruvate under aerobic condition 
> Glycolysis is conversion of glucose to lactate under anaerobic condition 
> Glycolysis occurs in cytosol 
> Glycolysis is regulated at three steps involving irreversible reactions catalysed by enzymes namely Hexokinase, Phosphofructokinase and Pyruvate kinase 
Glucokihase is present only in liver cells but hexokinase is present in almost all tissues